The interior ministry confirmed on Monday that gunfire has been heard inside the Kabul University compound in police district three of the Afghan capital.
Without giving further details, Interior Ministry spokesman Tariq Arian said Afghan security forces were watching the situation closely.
The area has been cordoned off by police, another security official said.
A professor at the Kabul University told DPA that no one knew what exactly happened but students were escaping from the compound.
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In 2016, at least 16 people were killed in an attack on the American University of Afghanistan in Kabul.
It started when a suicide bomber ploughed his explosive-packed vehicle into the wall of the university and several others stormed the university with automatic weapons.
Kabul University is one of the most creditable academic institutions in Afghanistan. (dpa/NAN)