The draw for the last 16 of the UEFA Europa League was conducted in Nyon, Switzerland on Friday with teams from nine different European nations.
Defending champions Sevilla were drawn against Spanish rivals Villarreal while Italian sides Fiorentina and AS Roma do battle.
Ajax was the only reigning league champion drawn from the pot, which included four other former winners Inter Milan, Sevilla, Zenit St. Petersburg and Napoli.
English Premier League representative Everton will face Ukrainian outfit Dynamo Kiev. The Toffees will host the first leg on 12 March at Goodison Park and then travel to Ukraine the following week.
The complete table of UEFA Europa League Round of 16 Draw
Villarreal vs Sevilla
Fiorentina vs Roma
Everton vs Dynamo Kyiv
Wolfsburg vs Inter
Napoli vs Dinamo Moskva
Dnipro vs Ajax
Zenit vs Torino
Club Brugge vs Beşiktaş