A research recently carried out in China has discovered that the coronavirus disease has mutated into at least 30 different strains.
Chinese scientist, Professor Li Lanjuan and colleagues from Zhejiang University in Hangzhou, China, carried out the study and published in a non-peer reviewed paper released on website medRxiv.org on Sunday.
The results showed that medical officials have vastly underestimated the overall ability of the virus to mutate, in findings that different strains have affected different parts of the world, leading to potential difficulties in finding a permanent cure.
According to the paper, “Sars-CoV-2 has acquired mutations capable of substantially changing its pathogenicity,” Li wrote.
The team further discovered that some of the mutations could lead to functional changes in the virus’ spike protein, the South China Morning Post reported. Spike protein is the protein that the coronavirus uses to attach itself to human cells.
In an experiment, Li ‘s team infected cells with COVID-19 strains carrying different mutations, of which the most aggressive strains were found to generate as much as 270 times as much viral load as the weakest strains. The aggressive strains also killed the human cells the fastest.
The results indicated “that the true diversity of the viral strains is still largely underappreciated,” Li wrote.
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The research could have future implications and shed more light on the treatment of coronavirus, as several different strains have been found throughout the world. The United States which has the world’s worst death toll at 42,897, and 799,515 overall cases, has been hit by different mutations of the virus. New York, which itself had the worst death rate in the US, and the eastern coast show a strain of coronavirus similar to that found in Europe, whereas the western US has shown similarities with strains found in China.
This new discovery shows a new direction in the fight as Coronavirus has so far been treated in hospitals worldwide as one disease and patients receive the same treatment regardless and unaware of the strain. It has been advised by the team at Zhejiang University that defining mutations in different regions may change the way we approach treating the virus
“Drug and vaccine development, while urgent, need to take the impact of these accumulating mutations into account to avoid potential pitfalls,” the scientists added.